Genetic Process For Dementia Identified


A study published in the journal Nature Medicine suggests progress in fighting dementia.

The study, conducted by a UCLA research team, identified two genetic processes involved in the neurodegeneration that occurs in dementia.

The study was done mostly in mouse models of dementia, but additional experiments showed the same genetic processes occur in human brains.

Researchers discovered two major groups of genes involved in mutations that result in an overproduction of tau, a sign of neurodegeneration.

The researchers then searched a database of experimental drugs and were able to identify molecules that interfere with neurodegeneration in human cell cultures.

More than five million people in the US have Alzheimer’s Disease or related dementia; a number that’s expected to triple by the year 2060.

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